Popeye Biotechnology (Shenzhen) Co.,Ltd.

Cefpodoxime Proxetil Impurities A

A.（6R,7R）-7-[[（2Z）-2-（2-aminothiazol-4-yl）-2-（methoxyimino）-acetyl]amino]-3-（methoxymethyl）-8-oxo-5-thia-1-azabicyclo-[4.2.0]oct-2-ene-2-carboxylic acid （cefpodoxime）

Cefpodoxime Proxetil Impurities B

B.（1RS）-1-[[（1-methylethoxy）carbonyl]oxy]ethyl（6R,7R）-7-[[（2Z）-2-（2-aminothiazol-4-yl）-2-（methoxyimino）acetyl]amino]-3-methyl-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate（ADCA-analogue of cefpodoxime proxetil）, 

Cefpodoxime Proxetil Impurities C

C.（1RS）-1-[[（1-methylethoxy）carbonyl]oxy]ethyl（6R,7R）-7-[[（2Z）-2-（2-aminothiazol-4-yl）-2-（methoxyimino）acetyl]amino]-3-（methoxymethyl）-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-3-ene-2-carboxylate （delta-2-cefpodoxime proxetil）

Cefpodoxime Proxetil Impurities D

D.（1RS）-1-[[（1-methylethoxy）carbonyl]oxy]ethyl（6R,7R）-7-[[（2E）-2-（2-aminothiazol-4-yl）-2-（methoxyimino）acetyl]amino]-3-（methoxymethyl）-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate （anti-cefpodoxime proxetil

Cefpodoxime Proxetil Impurities E

E.（1RS）-1-[[（1-methylethoxy）carbonyl]oxy]ethyl（6R,7R）-3-（acetoxymethyl）-7-[[（2Z）-2-（2-aminothiazol-4-yl）-2-（methoxyimino）acetyl]amino]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate （ACA-analogue of cefpodoxime proxetil）,

Cefpodoxime Proxetil Impurities F

F.（1RS）-1-[[（1-methylethoxy）carbonyl]oxy]ethyl-（6R,7R）-7-[[（2Z）-2-[（2-formylamino）thiazol-4-yl）-2-（methoxyimino）acetyl]amino]-3-（methoxymethyl）-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate （N-formyl cefpodoxime proxetil） 

Cefpodoxime Proxetil Impurities G

G.（1RS）-1-[[（1-methylethoxy）carbonyl]oxy]ethyl-（6R,7R）-7-[[（2Z）-[2-（2-acetylamino）thiazol-4-yl]-2-（methoxyimino）acetyl]amino]-3-（methoxymethyl）-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate （N-acetyl-cefpodoxime proxetil） 

Cefpodoxime Proxetil Impurities H

H. Mixture of the diastereoisomers of 1-[[（1-methylethoxy）carbonyl]oxy]ethyl（6R,7R）-7-[[（2Z）-2-[2-[[（2R）-2-[[（2Z）-2-（2-aminothiazol-4-yl）-2-（methoxyimino）acetyl]amino]-2-[（2R）-5-（methoxymethyl）-4-[[1-[[（1-methylethoxy）carbonyl]oxy]ethoxy]carbonyl]-3,6-dihydro-2H-1,3-thiazin-2-yl]acetyl]amino]thiazol-4-yl]-2-（methoxyimino）acetyl]amino]-3-（methoxymethyl）-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate （cefpodoxime proxetil dimer

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